Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
نویسندگان
چکیده
منابع مشابه
Platelet size, platelet surface-associated IgG, and reticulated platelets in dogs with immune-mediated thrombocytopenia.
Immune-mediated thrombocytopenia (IMT) is a disorder in which bound IgG on the surface of platelets results in platelet removal and alterations in mean platelet volume. Using flow cytometry, alterations in platelet size, platelet surface-associated IgG (PSAIgG), and numbers of reticulated platelets were determined in 13 dogs with primary IMT and 4 dogs with secondary IMT induced by experimental...
متن کاملReticulated platelet levels in whole blood and platelet-rich plasma of dogs with various platelet counts measured by flow cytometry.
Reticulated platelets (RP) are young platelets that contain residual RNA, and measurement of RP has been to assess thrombopoiesis. In the present study, flow cytometric counts of RP were compared using paired specimens elicited from dogs with various platelet counts by different RP collection procedures, the whole blood method (WBM) and platelet rich plasma method (PRPM). The flow cytometric co...
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At 8 and 32 hours after saphenous vein bypass graft surgery in six dogs, in vivo images of the graft were obtained with a gamma camera after intravenous injection, 2 hours postoperatively, of autologous platelets labeled with indium-111. Platelet deposition in the grafts could be imaged in vivo from the scintiphotos. In vitro images of the excised heart showed saphenous vein graft uptake confir...
متن کاملPlatelet Volume and Plateletcrit in Dogs with Presumed Primary Immune‐Mediated Thrombocytopenia
BACKGROUND Mean platelet volume (MPV) and plateletcrit (PCT) are indices used in evaluating immune-mediated thrombocytopenia (IMT) in humans and in dogs with congenital macrothrombocytopenia. These indices may provide clinically valuable information in acquired thrombocytopenia. HYPOTHESIS/OBJECTIVES Dogs with presumed primary IMT will have increased MPV, and therefore platelet mass (PCT) wil...
متن کاملApplication of vincristine-loaded platelet therapy in three dogs with refractory immune-mediated thrombocytopenia
Three dogs presented with refractory immune-mediated thrombocytopenia (IMT). All patients failed to respond to prednisone, which is considered a mainstay of immunosuppressive therapy. Vincristine-loaded platelets (VLPs), which act selectively on mononuclear phagocytes,were introduced. After the VLPs were transfused, two dogs responded quickly with improved clinical signs while the third dog wit...
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ژورنال
عنوان ژورنال: Archivos de medicina veterinaria
سال: 2016
ISSN: 0301-732X
DOI: 10.4067/s0301-732x2016000300005